Dr. Alexander Gorbach worked at the Institute of Higher Nervous Activity and Neurophysiology, USSR Academy of Sciences, Moscow, Russia, where he was awarded a PhD in human and animal physiology for design and validation of optical magneto-encephalography method. In 1991 Dr. Gorbach was invited to be a postdoctoral research fellow at the National Institute of Neurological Disorders and Stroke (NINDS), NIH, USA. His project was focused on clinical application of SQUID magneto-encephalography for cortical mapping. In 1992-1993 Dr. Gorbach was an Assistant Professor at the University of California School of Medicine at Los Angeles. In 1994-1995 he was a consultant for GE-Corporate Research & Development, Schenectady, New York, and for Hughes Research Laboratories, Malibu, California, USA. In 1995 Dr. Gorbach was invited to joint Surgical Neurology Branch, NINDS, NIH as a Special Expert. He was first to introduce intraoperative infrared functional imaging method capable to monitor the human cortex in real time. In 2000 he designed a procedure for objective, real-time, intraoperative assessment of perfusion during renal transplantation in human. In 2005 he described renal thermal oscillations during steady state and ischemic conditions in animals and humans. Currently, Dr. A Gorbach is a staff researcher and Chief of Unit at the National Institute of Biomedical Imaging and Bioengineering, NIH, USA. His main interests are in the areas of thermoregulation, functional connectivity of the brain, experimental evidence of complex dynamics, pattern formation, autoregulation and synchronization in microcirculation with applications to clinical research.
Plamen Ch. Ivanov
Professor Ivanov, PhD, DSc, is Director of the Keck Laboratory for Network Physiology at Boston University, Associate Physiologist at the Division of Sleep Medicine, Brigham and Women’s Hospital, and Lecturer in Medicine at Harvard Medical School. He has introduced innovative ways of analyzing and modeling physiologic systems, adapting and developing concepts and methods from modern statistical physics and nonlinear dynamics. He has investigated the complex dynamics and underlying control mechanisms of a range of physiological systems, including studies on cardiac and respiratory dynamics, sleep-stage transitions, circadian rhythms, locomotion and brain dynamics, and has uncovered basic laws of physiologic regulation. He is the originator and founder of the new emerging field of Network Physiology, to address the fundamental question of how diverse organ systems and sub-systems in the human body interact as a network and continuously coordinate, synchronize and integrate their functions to produce health and disease. Dr. Ivanov is one of the nine founding members of PhysioNet, an NIH sponsored data sharing research resource. His research has been funded by the W. M. Keck Foundation, NIH, Office of Naval Research (ONR) and the US-Israel Binational Science Foundation (BSF). For his achievements, Dr. Ivanov was elected Fellow of the American Physical Society in 2010. He is recipient of the Sustained Research Excellence Award (2009-2011) of the Biomedical Research Institute, Brigham and Women’s Hospital, Harvard Medical School; of the Georgi Nadjakov Medal, Bulgarian Academy of Sciences (2012), and of the Pythagoras Award for significant achievements in interdisciplinary research (2014). He served on several Editorial and Advisory Boards, including EPL (Europhysics Letters), EPJ Nonlinear Biomedical Physics, Journal of Biological Physics (JOBP), Frontiers in Fractal Physiology, Physiological Measurement
Professor Malberg, PhD, is Chair and Director of the Institute for Biomedical Engineering at Dresden University of Technology, Director of Steinbeis Research Center of Applied Biomedical Engineering, Dresden, and member of the Faculty of Electrical and Computer Engineering and the Medical Faculty “Carl Gustav Carus”, Germany. He received his PhD from Max-Delbrück-Center for Molecular Medicine in 1999. His work focuses on medical sensor technologies (contactless sensing, biosignal processing, decision support machines, automatic control in medicine, medical robotics, medical imaging and image processing) with clinical applications in cardiovascular medicine (cardiology, intensive care, cardiac surgery, sleep medicine), ambient assisted living, neurosurgery and rehabilitation medicine. He is the inventor of 17 patents. His vision is to support the development of a new generation of medical devices — being comfortable, reliable, clinical suitable and predictive, cheaper and mobile. Dr. Malberg is a member of IEEE-EMBS, German Society of Biomedical Engineering (DGBMT), European Society of Cardiology, German Hypertension League, European Sleep Research Society (ESRS). He is Chair of the 24th annual congress of the German Society of Sleep Research and Sleep Medicine (DGSM) 2016 and the Joint Congress of the German Society of Biomedical Engineering (DGBMT) and the German, Austrian and Swiss Societies of Medical Physics (DGMP) 2017.
J. Randall Moorman
Randall Moorman, M.D., is Professor of Medicine, Physiology, and Biomedical Engineering at the University of Virginia where he is a clinical cardiologist and founding Director of the UVa Center for Advanced Medical Analytics. He completed his undergraduate and medical degrees at the University of Mississippi, did clinical training at Duke Hospital where he was Chief Medical Resident, and undertook basic science research training at Baylor in molecular electrophysiology and membrane biophysics. His research focuses on bedside prediction of subacute, potentially catastrophic illnesses using advanced mathematical and statistical pattern recognition analyses of time series data from clinical monitors. His work initially centered on neonatal sepsis, a life-threatening infection of the bloodstream, and now on adult patient deterioration in ICUs and hospital wards. He developed sample entropy for use in physiological time series, and he introduced coefficient of sample entropy for detection of atrial fibrillation. He is an inventor on 9 issued US patents, the 2014 UVa Innovator of the Year, and Chief Medical Officer of Advanced Medical Predictive Devices, Diagnostics, and Displays. He is vice-president of the Society for Complex Acute Illness and Editor-in-Chief of Physiological Measurement.
Louis M. Pecora
Dr. Pecora is currently a research physicist at the Naval Research Laboratory, Washington, DC, where he heads the section for Magnetic Materials and Nonlinear Dynamics in the Materials and Sensors branch. He received his B.S. degree in physics from Wilkes College and he then enrolled in the Syracuse University Solid State Science program from which he received a Ph.D. in 1977. In the same year, he was awarded an NRC postdoctoral fellowship at the Naval Research Laboratory where he worked on applications of positron annihilation techniques in determining electronic states in copper alloys. This led to a permanent position at NRL. In the mid-1980’s Dr. Pecora moved into the field of nonlinear dynamics in solid state systems. Subsequent work has focused on the applications of chaotic behavior, especially the effects of driving systems with chaotic signals and coupling nonlinear dynamical systems in complex networks. This has resulted in the discovery of synchronization of chaotic systems, control and tracking, and dynamics of many coupled, nonlinear systems. Recently his research interests have turned to quantum chaos and collective behavior of oscillators in large complex networks, especially using the techniques of computational group theory. Dr. Pecora has published over 150 scientific papers and has 5 US patents for the applications of chaos. His original paper on the synchronization of chaotic systems has over 5000 citations and is the 10th most cited paper ever in Physical Review Letters. In 1995 he received the Sigma Xi award for Pure Science for the study of synchronization in chaotic systems.
Arkady S. Pikovsky
Professor Pikovsky, PhD, is Chair of the Departmant of Physics and Astronomy, University of Potsdam, Germany. He graduated from the Gorky State University (USSR) in 1987, and worked in the field of nonlinear dynamics and theory of chaos in the Institute of Applied Physics of the Soviet Academy of Sciences. In 1990-1992 was an Alexander von Humboldt fellow at the University of Wuppertal, Germany. Since 1992 he is with the University of Potsdam, first as a research fellow and since 1997 as Professor. His work is in the fields of space-time chaos, dynamical regimes at the border of chaos and order, synchronization theory, noise-induced effects in nonlinear systems, methods of nonlinear data analysis of complex systems, patterns and structures, nonlinear and chaotic effects in disordered Hamiltonian dynamics. He is co-author of three monographs: “Synchronization: A Universal Concept in Nonlinear Sciences”, together with M. Rosenblum and J. Kurths, published by CUP in 2001; “Strange Nonchaotic Attractors” together with U. Feudel and S. Kuznetsov, published by World Sci. in 2006; “Lyapunov Exponents” together with A. Politi, published by CUP in 2016, and of more than 250 papers in refereed journals. Current research interests include study of complex synchronization regimes in networks of dynamical systems, with applications to life sciences. He served as panel member of the German Science Foundation (DFG) for Statistical Physics and Nonlinear Dynamics. A. Pikovsky is Fellow of the American Physical Society and Chaotic and Complex Systems Editor of Journal of Physics A: Mathematical and Theoretical.
Professor Rosenblum, PhD, has been a research scientist and Professor in the Department of Physics and Astronomy, University of Potsdam, Germany, since 1997. His main research areas are nonlinear dynamics, synchronization theory, and time series analysis, with application to biological systems. The most important results include description of phase synchronization of chaotic systems, analysis of complex collective dynamics in large networks of interacting oscillators, development of feedback techniques for control of collective synchrony in neuronal networks (as a model of deep brain stimulation of parkinsonian patients), methods for reconstruction of oscillatory networks from observations, application of these methods to analysis of cardio-respiratory interaction in humans. He studied physics at Moscow Pedagogical University, and went on to work in the Mechanical Engineering Research Institute of the USSR Academy of Sciences, where he was awarded a PhD in physics and mathematics. He was a Humboldt fellow in the Max-Planck research group on nonlinear dynamics, and a visiting scientist at Boston University. He is a co-author (with A. Pikovsky and J. Kurths) of the book “Synchronization: A Universal Concept in Nonlinear Sciences”, Cambridge University Press, 2001 and has published over 100 peer-review publications, including 5 papers in the journals of the Nature Group and 11 papers in Physical Review Letters. Michael Rosenblum served as a member of the Editorial Board of Physical Review E. Since 2014 he is on the Editorial Board of Chaos: Int. J. of Nonlinear Science. He was named an American Physical Society Outstanding Referee for 2015.
Dr. Stramaglia is an Associate Professor of Applied Physics at the University of Bari, Italy, and External Scientific Member of the Basque Center for Applied Mathematics, Bilbao, Spain. He received his Ph.D. in Statistical Mechanics of random surfaces from the University of Bari in 1995, and the Laurea degree in models of strongly correlated electronic systems in 1991. Since 2001 he is a member of the Center of Excellence “Innovative Technologies for Signal Detection and Processing”, funded by the Italian Ministry for Scientific Research; since 2002 he is a member of the V National Scientific Commission of INFN-Istituto Nazionale di Fisica Nucleare, Italy. He chaired several international events, including “Modeling Migraine: from nonlinear dynamics to clinical neurology” July 2009, Berlin, and “Nonlinear dynamics in electronic systems” July 2013, Bari. Editor of the books “Modelling Biomedical Signals”, World Scientific 2002, and “Emergent Complexity from Nonlinearity, in Physics, Engineering and the Life Sciences”, Springer 2017. He has been visiting scientist at the Institute for Theoretical Physics NORDITA and at the Department of Data Analysis of the University of Gent, Belgium, and visiting professor at Biocruces Health Institute, Bilbao, Spain. Since 2003 he is team leader of the INFN project “Biological applications of Theoretical Physics Methods”. His research focuses on dynamical networks and Granger causality approaches to physiological interactions, in particular he developed a kernel approach for the inference of nonlinear coupling among dynamical systems with applications to brain function and brain-heart interactions.
Michael F. Shlesinger
Dr. Michael Shlesinger created the Nonlinear Physics program at the Office of Naval Research in 1983. That program initially focused on the concept of chaos and its applications, including health monitoring. The program now has an emphasis on device physics. Today research in the program includes network control and network-to-network interactions. His own research included work in the 70’s and 80’s on noise properties of potassium channels, and in the 2000’s the design of peptides to bind to G-7 transmembrane receptors. He has published over 200 scientific works on topics of fractals, Levy flights and other scale invariant phenomena from charge movement in amorphous semiconductors to turbulent diffusion. More recent work involves conductivity, dielectric relaxation, and viscosity of polymers as a function of temperature and pressure near the glass transition. He received the US Government Presidential Rank Award in 2004, ONR’s Saalfeld award for Outstanding Lifetime Achievement in Science in 2006, and in 2013 the American Physical Society Outstanding Referee Award. He is a Fellow of the APS and he held the Kinnear Chair in Physics at the US Naval Academy.
Robert J. Thomas
Robert Joseph Thomas, M.D., M.M.Sc, is Associate Professor of Medicine, Harvard Medical School & The Division of Pulmonary, Critical Care & Sleep, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA, His background includes Internal Medicine, Neurology and Sleep Medicine. His research spans mood, cognition (translational and epidemiology), sleep epidemiology, signal analysis in sleep medicine, and sleep-breathing outcomes, and functional imaging of cognition in sleep disorders. He has articulated a new approach to sleep physiology termed “sleep effectiveness”, which is a cross-physiology, networked, integrative approach to characterizing sleep state using cardiopulmonary coupling estimates (patented). His laboratory generates novel approaches and analysis tools for probing several sleep signals – ECG, EEG, respiration and multi-signal integration approaches. He funding sources are the NHLBI, NINDS and the American Sleep Medicine Foundation. He was key in the development of a FDA approved wearable device, the M1/SleepImage system, for dynamic sleep quality tracking. He is an acknowledged expert in the area of treatment of central and complex sleep apnea and periodic breathing, utilizing CO2 regulation approaches (patented). He studies brain health in the context of sleep disorders in the USA and South Korea. He directs the AASM accredited clinical sleep center and sleep laboratory, and the sleep medicine training program at the Beth Israel Deaconess Medical Center. I worked in the development and implementation (patented) of auto CPAP algorithms from concept through regulatory submission, which are now in FDA approved products.
Taylor Thompson, MD, is a Professor of Medicine at Harvard Medical School and the Director of Translational Research for the Division of Pulmonary and Critical Care Unit at the Massachusetts General Hospital (MGH), Boston. Dr Thompson served as the Director of the MGH Medical Intensive Care Unit for over 20 years and currently serves as an Associate Editor for Critical Care for the American Journal of Respiratory and Critical Care Medicine. Dr. Thompson is an expert in the design, conduct, and analysisof clinical trials for the critically ill and has coordinate a number of complex clinical trials that have influenced the care of patients with ARDS worldwide. He serves as Medical Director of the Clinical Coordinating Center for the NHLBI’s Prevention and Early Treatment of Acute Lung Injury (PETAL) Clinical Trials Network. This network is currently involved with three large randomized trials of for ARDS and sepsis and for the prevention of critical illness. In addition to ARDS, Dr. Thompson’s clinicaland research interests include functional imaging of the lung using positron emission tomography, diagnostic approaches to pulmonary thromboembolism, and the use of computerized decision support tools in the ICU.